Starships of the Ambassador class entered Starfleet service in the late 2320's and early 2330's. This class became the first new Federation starship class to have a computer network not based on duotronic technology in about 90 years. Along with a new computer system based on isolinear technology, the impulse engines of this class were designed with the first accelerator/generator along with a subspace field coil. Also, the warp propulsion system of the Ambassador class was the most efficient system in the Federation. The system was so efficient that the Federation had to recalibrate the warp scale that it used to determine warp factors. Originally categorized as an explorer, the Ambassador class received modifications in the 2350's and was re-categorized as a heavy cruiser during a time of conflict with the Cardassian Union/Empire, known as the Border Wars.
| ADELPHI | NCC-26849 |
| AMBASSADOR | NCC-10521 |
| ENTERPRISE | NCC-1701-C |
| EXCALIBUR | NCC-26517 |
| EXETER | NCC-26531 |
| GANDHI | NCC-26632 |
| HORATIO | NCC-10532 |
| VALDEMAR | NCC-26198 |
| YAMAGUCHI | NCC-26510 |
| ZHUKOV | NCC-26136 |
